OSMR HEK293
CBP74624
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| I. Background | |
| OSMR(抑瘤素M受体)由OSMR基因编码,是I型细胞因子受体家族成员。它作为IL-6信号转导子(IL6ST) 和IL-31受体A(IL31RA) 的共同伴侣,分别形成II型抑瘤素M(OSM)受体和IL-31受体,介导炎症、细胞生长调控和瘙痒等信号传导。该基因突变与家族性原发性局部皮肤淀粉样变(PLCA1)密切相关。 | |
| II. Description | |
| OSMR HEK293细胞,在 HEK293 细胞的基础上,稳定表达 OSMR 。 | |
| III. Introduction | |
| Expressed gene: | OSMR |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+ 5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant OSMR HEK293 constitutively expressing OSMR. |
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